埼玉医科大学総合医療センター

中央検査部

2017年以前　業績

英語論文

• Zhu E, Hu L, Wu H, Piao L, Zhao G, Inoue A, Kim W, Yu C, Xu W, Bando YK, Li X, Lei Y, Hao CN, Takeshita K, Kim WS, Okumura K, Murohara T, Kuzuya M, Cheng XW. Dipeptidyl Peptidase-4 Regulates Hematopoietic Stem Cell Activation in Response to Chronic Stress. Journal of the American Heart Association.6(7). 2017.
• Yisireyili M, Takeshita K, Saito S, Murohara T, Niwa T. Indole-3-propionic acid suppresses indoxyl sulfate-induced expression of fibrotic and inflammatory genes in proximal tubular cells. Nagoya journal of medical science.79(4):477-86. 2017.
• Yisireyili M, Hayashi M, Wu H, Uchida Y, Yamamoto K, Kikuchi R, Shoaib Hamrah M, Nakayama T, Wu Cheng X, Matsushita T, Nakamura S, Niwa T, Murohara T, Takeshita K. Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice. Scientific reports.7(1):1266. 2017.
• Takemoto Y, Horiba M, Harada M, Sakamoto K, Takeshita K, Murohara T, Kadomatsu K, Kamiya K. Midkine Promotes Atherosclerotic Plaque Formation Through Its Pro-Inflammatory, Angiogenic and Anti-Apoptotic Functions in Apolipoprotein E-Knockout Mice. Circ J.82(1):19-27. 2017.
• Sawamura A, Okumura T, Takeshita K, Watanabe N, Kano N, Mori H, Fukaya K, Morimoto R, Hirashiki A, Bando YK, Murohara T. Abnormal Circadian Blood Pressure Profile as a Prognostic Marker in Patients with Nonischemic Dilated Cardiomyopathy. Cardiology.136(1):1-9. 2017.
• Sawaguchi S, Varshney S, Ogawa M, Sakaidani Y, Yagi H, Takeshita K, Murohara T, Kato K, Sundaram S, Stanley P, Okajima T. O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals. eLife.6. 2017.
• Nakayama T, Mizutani K, Hanamura I, Kato H, Takami A, Takeshita K, Watanabe D. Livedoid vasculopathy and popliteal artery occlusion in a patient with protein S deficiency. The Journal of dermatology.44(2):198-201. 2017.
• Morimoto R, Okumura T, Hirashiki A, Ishii H, Ichii T, Aoki S, Furusawa K, Hiraiwa H, Kondo T, Watanabe N, Kano N, Fukaya K, Sawamura A, Takeshita K, Bando YK, Murohara T. Myocardial contractile reserve predicts left ventricular reverse remodeling and cardiac events in dilated cardiomyopathy. Journal of cardiology.70(4):303-9. 2017.
• Morimoto R, Okumura T, Bando YK, Fukaya K, Sawamura A, Kawase H, Shimizu S, Shimazu S, Hirashiki A, Takeshita K, Murohara T. Biphasic Force-Frequency Relation Predicts Primary Cardiac Events in Patients With Hypertrophic Cardiomyopathy. Circ J.81(3):368-75. 2017.
• Lei Y, Yang G, Hu L, Piao L, Inoue A, Jiang H, Sasaki T, Zhao G, Yisireyili M, Yu C, Xu W, Takeshita K, Okumura K, Kuzuya M, Cheng XW, Faha. Increased dipeptidyl peptidase-4 accelerates diet-related vascular aging and atherosclerosis in ApoE-deficient mice under chronic stress. Int J Cardiol.243:413-20. 2017.
• Kikuchi R, Yasuda Y, Nakatochi M, Shibata Y, Hara T, Suzuki A, Imaizumi T, Suzuki S, Ishii H, Takeshita K, Matsushita T, Maruyama S, Murohara T. Urinary and circulating levels of the anti-angiogenic isoform of vascular endothelial growth factor-A in patients with chronic kidney disease. Clinica chimica acta; international journal of clinical chemistry.475:102-8. 2017.
• Honda K, Takeshita K, Murotani K, Mitsuma A, Hayashi H, Tsunoda N, Kikumori T, Murohara T, Ando Y. Assessment of left ventricular diastolic function during trastuzumab treatment in patients with HER2-positive breast cancer. Breast cancer.24(2):312-8. 2017.
• Hirashiki A, Adachi S, Nakano Y, Kamimura Y, Shimokata S, Takeshita K, Shimizu A, Toba K, Murohara T, Kondo T. Circulatory power and ventilatory power over time under goal-oriented sequential combination therapy for pulmonary arterial hypertension. Pulmonary circulation.7(2):448-54. 2017.
• Fukaya K, Takeshita K, Okumura T, Hiraiwa H, Aoki S, Ichii T, Sugiura Y, Kitagawa K, Kondo T, Watanabe N, Kano N, Furusawa K, Sawamura A, Morimoto R, Bando Y, Murohara T. Sokolow-Lyon voltage is suitable for monitoring improvement in cardiac function and prognosis of patients with idiopathic dilated cardiomyopathy. Ann Noninvasive Electrocardiol.22(5). 2017.
• Yisireyili M, Takeshita K, Hayashi M, Wu H, Uchida Y, Yamamoto K, Kikuchi R, Hao CN, Nakayama T, Cheng XW, Matsushita T, Nakamura S, Murohara T. Dipeptidyl peptidase- IV inhibitor alogliptin improves stress-induced insulin resistance and prothrombotic state in a murine model. Psychoneuroendocrinology.73:186-95. 2016.
• Wu H, Cheng XW, Hu L, Takeshita K, Hu C, Du Q, Li X, Zhu E, Huang Z, Yisireyili M, Zhao G, Piao L, Inoue A, Jiang H, Lei Y, Zhang X, Liu S, Dai Q, Kuzuya M, Shi GP, Murohara T. Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K-Akt/p-HDAC6 Signaling Pathway. Arteriosclerosis, thrombosis, and vascular biology.36(8):1549-57. 2016.
• Sugimoto K, Miyata Y, Nakayama T, Saito S, Suzuki R, Hayakawa F, Nishiwaki S, Mizuno H, Takeshita K, Kato H, Ueda R, Takami A, Naoe T. Fibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions. Scientific reports.6:30779. 2016.
• Shoaib Hamrah M, Hashem Hamrah M, Ishii H, Suzuki S, Hussain Hamrah M, Hassan Hamrah M, Yisireyili M, Kano N, Takeshita K, Sakamoto J, Murohara T. Associations between proteinuria and cardiovascular risk factors among hypertensive patients in Andkhoy, Afghanistan. Nagoya journal of medical science.78(4):377-86. 2016.
• Niwa R, Nakayama T, Ishii H, Fujita E, Ishiyama K, Matsuo T, Shimizu A, Gao S, Hayashi M, Katai A, Ando T, Takahashi M, Takeshita K, Takami A, Kato H. Identification of a novel missense mutation (563G>a) in the ABO gene associated with a Bel phenotype. Transfusion.56(5):1242-3. 2016.
• Hirashiki A, Kondo T, Okumura T, Kamimura Y, Nakano Y, Fukaya K, Sawamura A, Morimoto R, Adachi S, Takeshita K, Murohara T. Cardiopulmonary Exercise Testing as a Tool for Diagnosing Pulmonary Hypertension in Patients with Dilated Cardiomyopathy. Ann Noninvasive Electrocardiol.21(3):263-71. 2016.
• Hirashiki A, Adachi S, Nakano Y, Kamimura Y, Shimokata S, Takeshita K, Murohara T, Kondo T. Effects of bosentan on peripheral endothelial function in patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension. Pulmonary circulation.6(2):168-73. 2016.
• Hayashi M, Takeshita K, Uchida Y, Yamamoto K, Matsushita T, Murohara T. Angiotensin receptor blocker improves a stress-induced prothrombotic state in a murine model. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.27(3):358-60. 2016.
• Uchida Y, Ichimiya S, Ishii H, Kanashiro M, Watanabe J, Hayano S, Suzuki S, Takeshita K, Sakai S, Amano T, Matsubara T, Murohara T. Impact of Admission Anemia on Coronary Microcirculation and Clinical Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Int Heart J.56(4):381-8. 2015.
• Takeshita K, Matsushita T, Murohara T. Asymptomatic left atrial thrombus in a dialysis-dependent patient free of thrombogenic abnormalities. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.19(1):93-4. 2015.
• Nagai H, Suzuki S, Ishii H, Shibata Y, Harata S, Takayama Y, Tatami Y, Shimbo Y, Osugi N, Ota T, Kawamura Y, Tanaka A, Takeshita K, Murohara T. Impact of low-grade albuminuria on left ventricular diastolic dysfunction. IJC Metabolic & Endocrine.6:13-6. English2015.
• Li X, Cheng XW, Hu L, Wu H, Guo P, Hao CN, Jiang H, Zhu E, Huang Z, Inoue A, Sasaki T, Du Q, Takeshita K, Okumura K, Murohara T, Kuzuya M. Cathepsin S activity controls ischemia-induced neovascularization in mice. Int J Cardiol.183:198-208. 2015.
• Hamrah MS, Suzuki S, Ishii H, Shibata Y, Tatami Y, Osugi N, Ota T, Kawamura Y, Tanaka A, Aso H, Takeshita K, Sakamoto J, Hasegawa Y, Murohara T. Impact of airflow limitation on carotid atherosclerosis in coronary artery disease patients. Respiration; international review of thoracic diseases.89(4):322-8. 2015.
• Yuasa D, Ohashi K, Shibata R, Takeshita K, Kikuchi R, Takahashi R, Kataoka Y, Miyabe M, Joki Y, Kambara T, Uemura Y, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Ito M, Ikeda N, Murohara T, Ouchi N. Association of circulating C1q/TNF-related protein 1 levels with coronary artery disease in men. PloS one.9(6):e99846. 2014.
• Yoshikawa D, Ishii H, Suzuki S, Takeshita K, Kumagai S, Hayashi M, Niwa T, Izawa H, Murohara T. Plasma indoxyl sulfate and estimated glomerular filtration rate. Circ J.78(10):2477-82. 2014.
• Yisireyili M, Saito S, Abudureyimu S, Adelibieke Y, Ng HY, Nishijima F, Takeshita K, Murohara T, Niwa T. Indoxyl sulfate-induced activation of (pro)renin receptor promotes cell proliferation and tissue factor expression in vascular smooth muscle cells. PloS one.9(10):e109268. 2014.
• Yamamoto K, Takeshita K, Saito H. Plasminogen activator inhibitor-1 in aging. Semin Thromb Hemost.40(6):652-9. 2014.
• Yamada T, Hirashiki A, Okumura T, Adachi S, Shimazu S, Shimizu S, Morimoto R, Takeshita K, Naganawa S, Kondo T, Murohara T. Prognostic impact of combined late gadolinium enhancement on cardiovascular magnetic resonance and peak oxygen consumption in ambulatory patients with nonischemic dilated cardiomyopathy. Journal of cardiac failure.20(11):825-32. 2014.
• Wu H, Cheng XW, Hu L, Hao CN, Hayashi M, Takeshita K, Hamrah MS, Shi GP, Kuzuya M, Murohara T. Renin inhibition reduces atherosclerotic plaque neovessel formation and regresses advanced atherosclerotic plaques. Atherosclerosis.237(2):739-47. 2014.
• Tatami Y, Suzuki S, Ishii H, Shibata Y, Osugi N, Ota T, Kawamura Y, Tanaka A, Takeshita K, Murohara T. Impact of serum bilirubin levels on carotid atherosclerosis in patients with coronary artery disease. IJC Metabolic & Endocrine.5:24-7. 2014.
• Tamai H, Kobayashi M, Takeshita K, Kodama A, Banno H, Narita H, Yamamoto K, Komori K. Possible involvement of Notch signaling in the pathogenesis of Buerger's disease. Surg Today.44(2):307-13. 2014.
• Takeshita K, Murohara T. Does angiotensin receptor blockade ameliorate the prothrombotic tendency in hypertensive patients with atrial fibrillation? Breaking the vicious cycle. Hypertension research : official journal of the Japanese Society of Hypertension.37(6):490-1. 2014.
• Nishiwaki S, Nakayama T, Murata M, Nishida T, Terakura S, Saito S, Kato T, Mizuno H, Imahashi N, Seto A, Ozawa Y, Miyamura K, Ito M, Takeshita K, Kato H, Toyokuni S, Nagao K, Ueda R, Naoe T. Dexamethasone palmitate ameliorates macrophages-rich graft-versus-host disease by inhibiting macrophage functions. PloS one.9(5):e96252. 2014.
• Jiang H, Cheng XW, Shi GP, Hu L, Inoue A, Yamamura Y, Wu H, Takeshita K, Li X, Huang Z, Song H, Asai M, Hao CN, Unno K, Koike T, Oshida Y, Okumura K, Murohara T, Kuzuya M. Cathepsin K-mediated Notch1 activation contributes to neovascularization in response to hypoxia. Nature communications.5:3838. 2014.
• Inaba H, Takeshita K, Uchida Y, Hayashi M, Okumura T, Hirashiki A, Yoshikawa D, Ishii H, Yamamoto K, Nakayama T, Hirayama M, Matsumoto H, Matsushita T, Murohara T. Recovery of flow-mediated vasodilatation after repetitive measurements is involved in early vascular impairment: comparison with indices of vascular tone. PloS one.9(1):e83977. 2014.
• Hirashiki A, Adachi S, Nakano Y, Kono Y, Shimazu S, Shimizu S, Morimoto R, Okumura T, Takeshita K, Yamada S, Murohara T, Kondo T. Cardiopulmonary exercise testing to evaluate the exercise capacity of patients with inoperable chronic thromboembolic pulmonary hypertension: an endothelin receptor antagonist improves the peak PETCO2. Life sciences.118(2):397-403. 2014.
• Hayashi M, Takeshita K, Uchida Y, Yamamoto K, Kikuchi R, Nakayama T, Nomura E, Cheng XW, Matsushita T, Nakamura S, Murohara T. Angiotensin II receptor blocker ameliorates stress-induced adipose tissue inflammation and insulin resistance. PloS one.9(12):e116163. 2014.
• Hayashi M, Kaneko S, Shimano M, Ohashi T, Kubota R, Takeshita K, Shinoda M, Inden Y, Kanayama H, Murohara T. Efficacy and safety of radiofrequency catheter ablation for atrial fibrillation in chronic hemodialysis patients. Nephrol Dial Transplant.29(1):160-7. 2014.
• Yoshikawa D, Ishii H, Kurebayashi N, Sato B, Hayakawa S, Ando H, Hayashi M, Isobe S, Okumura T, Hirashiki A, Takeshita K, Amano T, Uetani T, Yamada S, Murohara T. Association of cardiorespiratory fitness with characteristics of coronary plaque: assessment using integrated backscatter intravascular ultrasound and optical coherence tomography. Int J Cardiol.162(2):123-8. 2013.
• Yamada T, Hirashiki A, Cheng XW, Okumura T, Shimazu S, Okamoto R, Shinoda N, Isobe S, Takeshita K, Naganawa S, Kondo T, Murohara T. Relationship of myocardial fibrosis to left ventricular and mitochondrial function in nonischemic dilated cardiomyopathy--a comparison of focal and interstitial fibrosis. Journal of cardiac failure.19(8):557-64. 2013.
• Shimazu S, Hirashiki A, Okumura T, Yamada T, Okamoto R, Shinoda N, Takeshita K, Kondo T, Niwa T, Murohara T. Association between indoxyl sulfate and cardiac dysfunction and prognosis in patients with dilated cardiomyopathy. Circ J.77(2):390-6. 2013.
• Sato B, Yoshikawa D, Ishii H, Suzuki S, Inoue Y, Takeshita K, Tanaka M, Kumagai S, Matsumoto M, Okumura S, Hayashi M, Matsubara T, Niwa T, Murohara T. Relation of plasma indoxyl sulfate levels and estimated glomerular filtration rate to left ventricular diastolic dysfunction. Am J Cardiol.111(5):712-6. 2013.
• Sato B, Yoshikawa D, Ishii H, Kikuchi R, Arima T, Takeshita K, Inoue Y, Suzuki S, Tanaka M, Kumagai S, Matsumoto M, Hayashi M, Ando H, Amano T, Matsubara T, Niwa T, Murohara T. Indoxyl sulfate, a uremic toxin, and carotid intima-media thickness in patients with coronary artery disease. Int J Cardiol.163(2):214-6. 2013.
• Okumura T, Shimizu S, Fukaya K, Sawamura A, Morimoto R, Shimazu S, Hirashiki A, Takeshita K, Bando YK, Murohara T. [Assessment of cardiac contractile reserve]. Rinsho Byori.61(10):917-23. 2013.
• Okumura T, Hirashiki A, Yamada S, Funahashi H, Ohshima S, Kono Y, Cheng XW, Takeshita K, Murohara T. Association between cardiopulmonary exercise and dobutamine stress testing in ambulatory patients with idiopathic dilated cardiomyopathy: a comparison with peak VO(2) and VE/VCO(2) slope. Int J Cardiol.162(3):234-9. 2013.
• Okamoto R, Hirashiki A, Cheng XW, Yamada T, Shimazu S, Shinoda N, Okumura T, Takeshita K, Bando Y, Kondo T, Murohara T. Usefulness of serum cardiac troponins T and I to predict cardiac molecular changes and cardiac damage in patients with hypertrophic cardiomyopathy. Int Heart J.54(4):202-6. 2013.
• Fujita M, Cheng XW, Inden Y, Shimano M, Yoshida N, Inoue A, Yamamoto T, Takeshita K, Kyo S, Taguchi N, Shi GP, Kuzuya M, Okumura K, Murohara T. Mechanisms with clinical implications for atrial fibrillation-associated remodeling: cathepsin K expression, regulation, and therapeutic target and biomarker. Journal of the American Heart Association.2(6):e000503. 2013.
• Uchida Y, Takeshita K, Yamamoto K, Kikuchi R, Nakayama T, Nomura M, Cheng XW, Egashira K, Matsushita T, Nakamura H, Murohara T. Stress augments insulin resistance and prothrombotic state: role of visceral adipose-derived monocyte chemoattractant protein-1. Diabetes.61(6):1552-61. 2012.
• Uchida Y, Ichimiya S, Ishii H, Kanashiro M, Watanabe J, Yoshikawa D, Takeshita K, Sakai S, Amano T, Matsubara T, Murohara T. Impact of metabolic syndrome on various aspects of microcirculation and major adverse cardiac events in patients with ST-segment elevation myocardial infarction. Circ J.76(8):1972-9. 2012.
• Uchida Y, Ichimiya S, Ishii H, Kanashiro M, Watanabe J, Yoshikawa D, Takeshita K, Sakai S, Amano T, Matsubara T, Murohara T. Impact of plaque burden in the left main coronary artery determined by intravascular ultrasound on cardiovascular events in a Japanese population undergoing percutaneous coronary intervention. Am J Cardiol.109(3):352-8. 2012.
• Shinoda N, Hirashiki A, Okumura T, Okamoto R, Wu Cheng X, Kono Y, Takeshita K, Yamada S, Murohara T. Predictive value of heart rate recovery after exercise testing in addition to brain natriuretic peptide levels in ambulatory patients with nonischemic dilated cardiomyopathy. Ann Noninvasive Electrocardiol.17(4):378-86. 2012.
• Mizuno H, Nakayama T, Miyata Y, Saito S, Nishiwaki S, Nakao N, Takeshita K, Naoe T. Mast cells promote the growth of Hodgkin's lymphoma cell tumor by modifying the tumor microenvironment that can be perturbed by bortezomib. Leukemia.26(10):2269-76. 2012.
• Matsubara H, Takeshita K, Nakamura S, Murohara T, Miyachi S. Carotidynia with carotid arterial thrombosis. Annals of internal medicine.157(12):917-9. 2012.
• Tanaka M, Ishii H, Aoyama T, Takahashi H, Toriyama T, Kasuga H, Takeshita K, Yoshikawa D, Amano T, Murohara T. Ankle brachial pressure index but not brachial-ankle pulse wave velocity is a strong predictor of systemic atherosclerotic morbidity and mortality in patients on maintenance hemodialysis. Atherosclerosis.219(2):643-7. 2011.
• Takeshita K, Inden Y, Murohara T. Coincidental finding of isolated congenital double-orifice mitral valve in two adult patients. European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology.12(3):E26. 2011.
• Shibata R, Ouchi N, Kikuchi R, Takahashi R, Takeshita K, Kataoka Y, Ohashi K, Ikeda N, Kihara S, Murohara T. Circulating omentin is associated with coronary artery disease in men. Atherosclerosis.219(2):811-4. 2011.
• Kurebayashi N, Yoshikawa D, Ishii H, Sato B, Ando H, Okada T, Hayakawa S, Okumura N, Isobe S, Takeshita K, Hayashi M, Uetani T, Amano T, Murohara T. Impact of the low- to high-density lipoprotein cholesterol ratio on composition of angiographically ambiguous left main coronary artery plaque. Circ J.75(8):1960-7. 2011.
• Kikuchi R, Takeshita K, Uchida Y, Kondo M, Cheng XW, Nakayama T, Yamamoto K, Matsushita T, Liao JK, Murohara T. Pitavastatin-induced angiogenesis and arteriogenesis is mediated by Notch1 in a murine hindlimb ischemia model without induction of VEGF. Laboratory investigation; a journal of technical methods and pathology.91(5):691-703. 2011.
• Hayashi M, Takeshita K, Inden Y, Ishii H, Cheng XW, Yamamoto K, Murohara T. Platelet activation and induction of tissue factor in acute and chronic atrial fibrillation: involvement of mononuclear cell-platelet interaction. Thromb Res.128(6):e113-8. 2011.
• Cheng XW, Kuzuya M, Sasaki T, Inoue A, Hu L, Song H, Huang Z, Li P, Takeshita K, Hirashiki A, Sato K, Shi GP, Okumura K, Murohara T. Inhibition of mineralocorticoid receptor is a renoprotective effect of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pitavastatin. J Hypertens.29(3):542-52. 2011.
• Nishizawa T, Cheng XW, Jin Z, Obata K, Nagata K, Hirashiki A, Sasaki T, Noda A, Takeshita K, Izawa H, Shi GP, Kuzuya M, Okumura K, Murohara T. Ca(2+) channel blocker benidipine promotes coronary angiogenesis and reduces both left-ventricular diastolic stiffness and mortality in hypertensive rats. J Hypertens.28(7):1515-26. 2010.
• Koyasu M, Ishii H, Watarai M, Takemoto K, Inden Y, Takeshita K, Amano T, Yoshikawa D, Matsubara T, Murohara T. Impact of acarbose on carotid intima-media thickness in patients with newly diagnosed impaired glucose tolerance or mild type 2 diabetes mellitus: A one-year, prospective, randomized, open-label, parallel-group study in Japanese adults with established coronary artery disease. Clin Ther.32(9):1610-7. 2010.
• Ii M, Takeshita K, Ibusuki K, Luedemann C, Wecker A, Eaton E, Thorne T, Asahara T, Liao JK, Losordo DW. Notch signaling regulates endothelial progenitor cell activity during recovery from arterial injury in hypercholesterolemic mice. Circulation.121(9):1104-12. 2010.
• Yamamoto K, Takeshita K, Kojima T, Takamatsu J. Stress-induced PAI-1 expression is suppressed by pitavastatin in vivo. International journal of hematology.89(4):553-4. 2009.
• Yamamoto K, Shibayama S, Takeshita K, Kojima T, Takamatsu J. A novel cholesterol absorption inhibitor, ezetimibe, decreases adipose-derived and vascular PAI-1 expression in vivo. Thromb Res.124(5):644-5. 2009.
• Li Y, Takeshita K, Liu PY, Satoh M, Oyama N, Mukai Y, Chin MT, Krebs L, Kotlikoff MI, Radtke F, Gridley T, Liao JK. Smooth muscle Notch1 mediates neointimal formation after vascular injury. Circulation.119(20):2686-92. 2009.
• Cheng XW, Okumura K, Kuzuya M, Jin Z, Nagata K, Obata K, Inoue A, Hirashiki A, Takeshita K, Unno K, Harada K, Shi GP, Yokota M, Murohara T. Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers. J Cardiovasc Pharmacol.54(1):47-56. 2009
• Aoyama T, Takeshita K, Kikuchi R, Yamamoto K, Cheng XW, Liao JK, Murohara T. gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice. Biochemical and biophysical research communications.383(2):216-21. 2009.
• Yamamoto K, Kojima T, Takeshita K, Matsushita T, Takamatsu J. Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice. Thromb Res.120(1):143-4. 2007.
• Takeshita K, Satoh M, Ii M, Silver M, Limbourg FP, Mukai Y, Rikitake Y, Radtke F, Gridley T, Losordo DW, Liao JK. Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circulation research.100(1):70-8. 2007.
• Satoh M, Matter CM, Ogita H, Takeshita K, Wang CY, Dorn GW, 2nd, Liao JK. Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen. Circulation.115(25):3197-204. 2007.
• Satoh M, Ogita H, Takeshita K, Mukai Y, Kwiatkowski DJ, Liao JK. Requirement of Rac1 in the development of cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America.103(19):7432-7. 2006.
• Mukai Y, Rikitake Y, Shiojima I, Wolfrum S, Satoh M, Takeshita K, Hiroi Y, Salomone S, Kim HH, Benjamin LE, Walsh K, Liao JK. Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt. The Journal of clinical investigation.116(2):334-43. 2006.
• Hayashi M, Matsushita T, Mackman N, Ito M, Adachi T, Katsumi A, Yamamoto K, Takeshita K, Kojima T, Saito H, Murohara T, Naoe T. Fatal thrombosis of antithrombin-deficient mice is rescued differently in the heart and liver by intercrossing with low tissue factor mice. Journal of thrombosis and haemostasis : JTH.4(1):177-85. 2006.
• Yamamoto K, Takeshita K, Kojima T, Takamatsu J, Saito H. Aging and plasminogen activator inhibitor-1 (PAI-1) regulation: implication in the pathogenesis of thrombotic disorders in the elderly. Cardiovascular research.66(2):276-85. 2005.
• Limbourg FP, Takeshita K, Radtke F, Bronson RT, Chin MT, Liao JK. Essential role of endothelial Notch1 in angiogenesis. Circulation.111(14):1826-32. 2005.
• Yamada K, Hirai M, Abe K, Ishihara H, Takeshita K, Takada Y, Mutoh M, Noda H, Shimizu A, Shibata Y, Yamada T, Kondo T, Yoshida Y, Inden Y, Murohara T. Diagnostic usefulness of postexercise systolic blood pressure response for detection of coronary artery disease in patients with echocardiographic left ventricular hypertrophy. Can J Cardiol.20(7):705-11. 2004.
• Takeshita K, Hayashi M, Iino S, Kondo T, Inden Y, Iwase M, Kojima T, Hirai M, Ito M, Loskutoff DJ, Saito H, Murohara T, Yamamoto K. Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction. The American journal of pathology.164(2):449-56. 2004.
• Takeshita K, Fujimori T, Kurotaki Y, Honjo H, Tsujikawa H, Yasui K, Lee JK, Kamiya K, Kitaichi K, Yamamoto K, Ito M, Kondo T, Iino S, Inden Y, Hirai M, Murohara T, Kodama I, Nabeshima Y. Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression. Circulation.109(14):1776-82. 2004.
• Matsushita T, Hayashi H, Kunishima S, Hayashi M, Ikejiri M, Takeshita K, Yuzawa Y, Adachi T, Hirashima K, Sone M, Yamamoto K, Takagi A, Katsumi A, Kawai K, Nezu T, Takahashi M, Nakashima T, Naoe T, Kojima T, Saito H. Targeted disruption of mouse ortholog of the human MYH9 responsible for macrothrombocytopenia with different organ involvement: hematological, nephrological, and otological studies of heterozygous KO mice. Biochemical and biophysical research communications.325(4):1163-71. 2004.
• Kondo T, Hayashi M, Takeshita K, Numaguchi Y, Kobayashi K, Iino S, Inden Y, Murohara T. Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers. Arteriosclerosis, thrombosis, and vascular biology.24(8):1442-7. 2004.
• Yamada T, Takagi A, Takeshita K, Yamamoto K, Ito M, Matsushita T, Murate T, Saito H, Kojima T. Enzyme immunoassay for measurement of murine plasminogen activator inhibitor-1, employing a specific antibody produced by the DNA vaccine method. Thromb Res.111(4-5):285-91. 2003.
• Yamamoto K, Takeshita K, Shimokawa T, Yi H, Isobe K, Loskutoff DJ, Saito H. Plasminogen activator inhibitor-1 is a major stress-regulated gene: implications for stress-induced thrombosis in aged individuals. Proceedings of the National Academy of Sciences of the United States of America.99(2):890-5. 2002.
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